• Latest
  • Trending
  • All

An opportunity to advance skin cancer treatment

August 8, 2021
New Printable, Injectable Materials for Advanced Medical Applications

New Printable, Injectable Materials for Advanced Medical Applications

May 29, 2025
Metal fleece: material for the batteries of the future

Metal fleece: material for the batteries of the future

May 24, 2025
AI and X-ray Vision to Gain Insight into Battery Electrolyte.

AI and X-ray Vision to Gain Insight into Battery Electrolyte

May 23, 2025
Mask users can now breathe easy on two counts

Mask users can now breathe easy on two counts

May 23, 2025
Boosting Cancer Treatment.

Boosting Cancer Treatment

May 23, 2025
Emergence Quantum: a commercial quantum research 'special ops' team

Emergence Quantum: a commercial quantum research ‘special ops’ team

May 22, 2025
Sugar-coated nanotherapy dramatically improves neuron survival in Alzheimer’s model.

Sugar-coated nanotherapy improves neuron survival

May 15, 2025
Quantum simulation of chemical dynamics achieved for first time

Quantum simulation of chemical dynamics achieved for first time

May 15, 2025
The mysterious chemical world inside nanopores.

The Mysterious Chemical World Inside Nanopores

May 13, 2025
Stability solution brings unique form of carbon closer to practical application.

Stability solution brings unique form of carbon closer to practical application

May 10, 2025
It’s Hard to Get Meds to the Lungs: Breathable Algae Offers a New Path.

It’s Hard to Get Meds to the Lungs: Breathable Algae Offers a New Path

May 7, 2025
New Bayesian Method Enables Rapid Detection of Quantum Dot Charge States

New Bayesian Method Enables Rapid Detection of Quantum Dot Charge States

May 2, 2025
  • About
  • Advertise
  • Privacy Policy
  • Terms & Conditions
  • Contact
Tuesday, June 3, 2025
  • Login
  • Register
Nanodigest
  • Home
  • Categories
    • Biological Science & Technology
    • Chemical Science & Technology
    • Material Science & Technology
    • Physical Science & Technology
    • Innovations & Education
  • NanoDigestExclusive
    AI and X-ray Vision to Gain Insight into Battery Electrolyte.

    AI and X-ray Vision to Gain Insight into Battery Electrolyte

    Emergence Quantum: a commercial quantum research 'special ops' team

    Emergence Quantum: a commercial quantum research ‘special ops’ team

    Couple satisfaction linked to fewer cognitive issues with chemo

    Ultrasound and Cilia to Clean Implanted Stents and Catheters

    Ultrasound and Cilia to Clean Implanted Stents and Catheters

    Celebrating Science

    Nobel prize for a New Way in Cancer Treatment

    Nobel prize for New Way in Cancer Treatment

    Simple to use device. Nano Digest.

    Simple to Use Device

    Nanofoam: Breakthrough in Material Design. Nano Digest.

    Nanofoam: Breakthrough in Material Design

    The Future of Solar Energy. Nano Digest.

    The Future of Solar Energy

    Trending Tags

    • 2D nanospace
    • 3D nano structures
    • Bacterial magnetic nanoparticle
    • Creation of nano technology
    • nano particles
    • Nano Technology
    • Nano Tv
    • nanomaterials
    • nanoparticles
    • Nanosciences
    • nanotubes
    • Nanowire
  • Nano TvYouTube
    Nanotechnology in Engineering – NANOENGINEERING | Nano Tv

    Nanotechnology in Engineering – NANOENGINEERING | Nano Tv

    nanotechnology, materials, graphene, nano digest, NanoTV

    Nanotechnology in Materials – GRAPHENE | Nano Tv

    Nanotechnology in Electronics - NANOELECTRONICS | Nano Tv, Nano Digest

    Nanotechnology in Electronics-NANOELECTRONICS | Nano Tv

    Nanotechnology in Medicine - NANOMEDICINE, Nano Tv, nano digest

    Nanotechnology in Medicine-NANOMEDICINE | Nano Tv

    Molecular Nanotechnology-NANOTECHNOLOGY & IMPLEMENTATIONS | Nano Tv, It deals with engineering nanoscale machines that operate on the molecular scale distinct from other areas of nanotechnology, such as nanoscale materials, nano digest

    Molecular Nanotechnology-NANOTECHNOLOGY & IMPLEMENTATIONS | Nano Tv

    What are Nanoparticles?, nano digest

    What are NANOPARTICLES?: Nano Tv

    THE ORIGIN & CHALLENGE by Richard Feynman | Nano Tv

    THE ORIGIN & CHALLENGE by Richard Feynman: Nano Tv

    Introduction, NANOTECHNOLOGY, nano digest, Nano Tv

    Introduction to NANOTECHNOLOGY | Nano Tv

  • ShopSale
No Result
View All Result
Nanodigest
No Result
View All Result
Home Chemical Science & Technology

An opportunity to advance skin cancer treatment

by Nano Digest
August 8, 2021
in Chemical Science & Technology
0
491
SHARES
1.4k
VIEWS
Share on FacebookShare on TwitterShare on Whatsapp

Novel and emerging nanotechnology approaches used in the treatment of skin cancer are generating interest as they enable the efficient delivery of drugs and other bioactive molecules to target tissues with low toxic effects. A recent study1 examined current investigations of nanoparticle and nanosystems and highlighted the therapeutic benefit and potentially larger role in the treatment of skin cancer.

Depending on disease stage, melanoma and nonmelanoma skin cancers can be treated in a variety of ways. However, the limitations of some treatment modalities have led research to explore new delivery systems and approaches to help improve clinical outcomes.

“The molecular mechanisms of melanoma have not been entirely elucidated; therefore, treating the disease is difficult. To overcome this challenge, innovative therapies are required that are mainly based on delivery systems using nanotechnology,” writes Livia Neves Borgheti-Cardoso, Ph.D., School of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paolo, Ribeirao Preto, San Paolo, Brazil, and fellow colleagues, in a study published in Advanced Drug Delivery Reviews.

One of the many recent advancements in the treatment of cancer has been nanotechnology and the nanosystems that they employ. Nanoparticles efficiently deliver therapeutic agents to the tumor site which can include chemotherapeutics, immune and vaccine molecules, and nucleic acids.

“Nanosystems can be developed to overcome biological barriers and to target drug delivery to the tumor sites, thus enabling the use of lower doses, increasing treatment efficacy and decreasing the number and/or the severity of the side effects,” the study authors write.

Most nanotechnology approaches and systems are still in the research and development phase; however, some have reached the clinical stage and are currently available on the market. There are no commercially available nanosystems to date for bioactive molecule topical delivery for skin cancer, the study authors write that some nanoparticle applications and products are being evaluated in clinical trials for advanced solid tumors as well as nonmelanoma skin cancers. The latter is a dose-rising study2 currently underway evaluating a topical nanoparticle paclitaxel ointment for safety, tolerability, and the preliminary efficacy of three concentrations (0.15 percent, 1.0 percent, and 2.0 percent) of the nanoparticle for the treatment of cutaneous metastases from nonmelanoma skin cancer.

Nanoparticles are currently being investigated to enhance the drug delivery of different agents in skin cancer therapies such as chemotherapy, immunotherapy including the PD-1 inhibitors, as well as therapeutic vaccines, with the hope of promoting more robust antitumor effects and improved clinical outcomes.

In cancer immunotherapy, nanoparticles can be directed to different cells and tissues related to the immune response including antigen presenting cells, lymphocytes and lymphoid tissues, thereby overcoming the limitations of direct cancer cell targeting. According to the study authors, one important advantage of using nanoparticles for antigen delivery is their capability to carry several adjuvants or neoantigens, which is ideal for treating different cancers.

When used in combination with physical techniques, nanocarriers could also help enhance topical and transdermal drug delivery in the treatment of melanoma and nonmelanoma skin cancers. Physical enhancement methods used include laser irradiation (i.e., phototherapy, thermotherapy, and acoustic therapy), iontophoresis, ultrasound, and microneedling systems.

A promising alternative for overcoming multidrug resistance, the authors explained that nanotechnology can also help the clinician provide treatment in a specific and orderly fashion, with smaller doses of therapeutic agents and fewer toxic effects.

“The use of nanocarriers enables the effective, targeted delivery of several therapeutic agents made from combinations of molecules aimed at acting synergistically and effectively against cancer types that are resistant and no longer responsive to conventional therapies,” the authors write.

Nanoparticles also used together with high-cost therapies including immunotherapies and gene therapies enable a more efficient administration of treatment, which can result in a more cost-effective approach and improved clinical outcomes.

“The versatility of these nanocarriers grows exponentially because although their use adds to the cost of therapy, it comes with innumerable benefits, which in terms of cost-effectiveness, are worth conceding, as these benefits lead to greater prospects for diagnosis and treatments, in addition to allowing the use of theranostics in cancer patients,” the study authors say.

Tags: Professor
Share196Tweet123Send
Nano Digest

Nano Digest

  • Trending
  • Comments
  • Latest

Nanotechnology in Cancer

September 10, 2020
Emergence of 2.5D Materials for Futuristic Applications

Emergence of 2.5D Materials for Futuristic Applications

June 29, 2022
New research methods developed for nano and quantum materials. Nano Digest.

New research methods developed for nano and quantum materials

February 24, 2023
Designing Gas detecting devices using nanomaterials. Nano Digest.

Designing Gas detecting devices using nanomaterials

2
3D Printing Allows Precise Light Control for Color Composition. nano Digest.

3D Printing Allows Precise Light Control for Color Composition

2

Wearable sensor monitors health, administers drugs using saliva and tears

1
New Printable, Injectable Materials for Advanced Medical Applications

New Printable, Injectable Materials for Advanced Medical Applications

May 29, 2025
Metal fleece: material for the batteries of the future

Metal fleece: material for the batteries of the future

May 24, 2025
AI and X-ray Vision to Gain Insight into Battery Electrolyte.

AI and X-ray Vision to Gain Insight into Battery Electrolyte

May 23, 2025
Nanodigest

Copyright © 2009-2022 NanoDigest.in

Navigate Site

  • About
  • Advertise
  • Privacy Policy
  • Terms & Conditions
  • Contact

Follow Us

No Result
View All Result
  • Home
  • Biological Science & Technology
  • Chemical Science & Technology
  • Material Science & Technology
  • Physical Science & Technology
  • Innovations & Education
  • NanoDigest Exclusive
  • Nano Tv
  • —————————–
  • About
  • Advertise
  • Contact
  • Privacy Policy
  • Terms & Conditions

Copyright © 2009-2022 NanoDigest.in

Welcome Back!

Sign In with Google
OR

Login to your account below

Forgotten Password? Sign Up

Create New Account!

Sign Up with Google
OR

Fill the forms below to register

*By registering into our website, you agree to the Terms & Conditions and Privacy Policy.
All fields are required. Log In

Retrieve your password

Please enter your username or email address to reset your password.

Log In
We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking “Accept All”, you consent to the use of ALL the cookies. However, you may visit "Cookie Settings" to provide a controlled consent.
Cookie SettingsAccept All
Manage consent

Privacy Overview

This website uses cookies to improve your experience while you navigate through the website. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may affect your browsing experience.
Necessary
Always Enabled
Necessary cookies are absolutely essential for the website to function properly. These cookies ensure basic functionalities and security features of the website, anonymously.
CookieDurationDescription
cookielawinfo-checkbox-analytics11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Analytics".
cookielawinfo-checkbox-functional11 monthsThe cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional".
cookielawinfo-checkbox-necessary11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary".
cookielawinfo-checkbox-others11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other.
cookielawinfo-checkbox-performance11 monthsThis cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Performance".
viewed_cookie_policy11 monthsThe cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data.
Functional
Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features.
Performance
Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors.
Analytics
Analytical cookies are used to understand how visitors interact with the website. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc.
Advertisement
Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. These cookies track visitors across websites and collect information to provide customized ads.
Others
Other uncategorized cookies are those that are being analyzed and have not been classified into a category as yet.
SAVE & ACCEPT
This website uses cookies. By continuing to use this website you are giving consent to cookies being used. Visit our Privacy and Cookie Policy.