Holographic devices (Biocompatible binary hologram with drug-elution capability) are used to increase security, entertainment, 3D viewing technology and augmented reality, but are not limited to them. Thanks to their high information capacity, ability to monitor continuous external processes by evaluating changes in the diffraction pattern, as well as proven and simple methods of their production from various materials, holograms find new applications in various fields of science and life.
In a new article (Biocompatible binary hologram with drug-elution capability) published by Light Science & Application (“Integrated Binary Hologram to Control the Release of Drug-Releasing Film“), a group of scientists developed a new production routine and application of holograms with only binary amplitude. The proposed direct drug printing (DDP) technique can be applied to water-soluble substances, but can be adapted to other types of drugs if necessary.
In numbers and experiments, they demonstrated the ability of the diffraction pattern to show the number of charges in a hologram after several hours. This unique feature of holographic packaging systems can be used in a wide variety of tasks that require control of the amount of substance released.
The authors summarize their research as follows:
“We are introducing an additive approach to the production of biocompatible DOE with direct drug printing (DDP). Bioactive substances are heat printed on the surface of a flat polymer film rather than charge bits. solvent and is placed “as is” in an inert biopolymer, which ensures that there are no changes in the pharmacological effect of the drug “predicted by the scientists.” “The resulting film acts as a transmissive amplitude hologram.
This payload packaging system, which produces a clear far-field diffraction pattern when powered by an identical light source, finds its place in various biomedical problems. The direct application of payload holograms is to monitor colorless content and measure natural release time of active substances under different conditions.-different environmental conditions. The most likely use of our technology is to complete a standard antibiotic testing procedure. Visual added channel for drug release control, which requires only the presence of an equivalent light source, further improves the evaluation of antibiotic effect and allows visual control release times and the amount of charge eluted,” they added.
