Previous studies have generally used nanozymes as antibacterial materials. However, the nanoparticles depend on H2O2, O2, superoxide, and hydroxyl radicals to generate reactive oxygen species, which hinders their use in anoxic environments. Recently prof. Zhang Dan from the Institute of Oceanography, Chinese Academy of Sciences (IOCAS) found that a persulfate-activated disposable material on MoS2 nanosheets can provide effective anaerobic microbial (A new “nano-killer” for sterilization and under painting) disinfection.
The study was published Aug. 9 in the Journal of Hazardous Materials.
The researchers created a fast and efficient (A new “nano-killer” for sterilization and under painting) anaerobic bacterial sterilization system with MoS2 nanosheets by exploiting the synergistic effect between physical damage and chemical oxidation. For physical damage, the negative sulfur of MoS2 can easily bind to the hydrophilic head of lipids, and the edge of MoS2 can cut the cell membrane like a “knife”. Based on density functional calculations, the researchers found that MoS2 nanosheets can catalyze persulfate and HO to produce oxidatively active species (OAS). These OAS can be considered as “nano-assassins” that continuously oxidize the lipids around MoS2, again exposing the “knife” surface, causing cell death. “Using the synergy between physical damage and chemical elimination, MoS2 has highly exposed active sites and tunable S vacancies, creating a platform that promotes the production of ‘nanokillers‘. The increased production of these free radicals and their close association with bacteria Contact allows rapid and stable sterilization in a variety of environments ,” said Jin Wang, first author of the study. “This work will open new horizons for anaerobic sterilization mechanisms and innovative disinfection strategies,” said prof. Zhang. The process of combining physical extraction with chemical oxidation not only enables precise placement of cell membranes, but also ensures continuous sterilization. “This work provides an in-depth study of the mechanisms by which anaerobic bacteria destroy bacteria, with implications for bio assays, antibacterial, cancer therapy and antimicrobial corrosion,” said the professor. Wang Yi, corresponding author of the study.
